Welcome to the NanoBioSens Lab

RESEARCH
We do research in an interdisciplinary field of Nanotechnology, Biotechnology, and Pharmacy to provide pertinent solutions to healthcare
Our research interest lies in interdisciplinary fields like Medical Device Development technology, NanoBiotechnology, BioNanoSensors, NanoDiagnostics, Preformulation and Formulation Development, Drug Delivery, etc.

MEDICAL DEVICE DEVELOPMENT
We are aiming to develop the medical devices for disease diagnostics and therapeutics. The devices that are affordable to the needy population, easy-to-use and portable will be made available to be used in remote or resource-limited settings.
NANOBIOTECHNOLOGY
We work on the synthesis of various nanoparticles including semiconductor nanocrystals i.e. Quantum Dots. The biofunctionalization of nanoparticles improves their utility in the development of biosensors.


POINT-OF-CARE TECHNIQUES
We have expertise in the development of lateral flow immunoassays and portable electronic devices required for the signal processing and analysis. Sensor-based colorimeter, as well as the fluorimeter, have been developed earlier.
DRUG DELIVERY
We work on the designing and development of novel drug delivery systems. Polymeric microparticles, nanoparticles, gel complex, composites, etc. are encapsulated or loaded with drugs and their efficacy is evaluated in vitro and in vivo.

PROJECTS
Role - Project Incharge
(2014-2017)
PI - Prof Rohit Srivastava, BSBE
IIT Bombay
A novel point of care detection device using nanotechnology for diagnosing periprosthetic infection following orthopedic surgery
Role - Investigator
(2013-2018)
PI - Prof Rohit Srivastava, BSBE
IIT Bombay
Nanodiagnostics for Orthopedic Implant-associated Infection
Role - Principal Investigator
(2018-2023)
IIT Guwahati (2018-2021),
NIPER Hyderabad (Current)
Lateral Flow Immunoassay based Point-of-Care Oral Cancer Diagnostic kit (OCDk)
PEOPLE
A Collaborative & Diverse Group
Our people are at the core of what makes the NanoBioSens such a unique and fulfilling place to work. We’re proud of the diversity of our staff, with each member contributing their unique skills to the projects we’re working on. Together, we’ve planned and executed some of the most innovative and cutting-edge experiments. Find out more about our team members below.
AWARDS AND RECOGNITION
“Award for Excellence in Thesis Work” (certificate and cash of INR 20,000) for the year 2016-2018 for outstanding research contributions in the Ph. D. The award was presented by the Hon. Prime Minister of India, Mr. Narendra Modi in the 56th Convocation of IIT Bombay (August 2018)
“INSPIRE FACULTY AWARD 2018” by Department of Science and Technology (DST), Govt of India (July 2018)
Selected as “Bentham Ambassador” for Bentham Journals by Bentham Science Publishers (December 2017)
“Student's Excellence Award” (certification and cash of INR 50,000) for 2016-17 by Lions Club of North Bombay (November 2017)
Invited Innovator at “Innovations in Medical Science and Biotechnology" during Festival of Innovations held on the lawns of Rashtrapati Bhavan (Presidential Palace), New Delhi (March 2017)
Awarded International Travel Grant by IIT Bombay, DST, and DBT, Govt. of India (February 2016)
DBT Tata Innovation Fellowship – served as Project Incharge (2014 – 2017)
“Merit Award Poster Presenter” at H3C conference organized by The Ohio State University in collaboration with AIIMS New Delhi held at Taj Mahal Palace Hotel, Mumbai (January 2015)
Won “Best Image Competition” (for FEG-SEM instrument imaging) organized by SAIF, CRNTS, IIT Bombay, Powai, Mumbai (December 2014)
Won 3rd prize (certification and cash of INR 2 Lakhs) in ABLE-BEST INDIA 2014 Entrepreneurship Workshop at Bangalore (October 2014)
Fellowship from Department of Biotechnology (DBT), Govt of India for Ph. D. program (2013-2018)
Ranked 3rd in M. Tech specialization, NIPER Mohali (July 2012)
CSIR-UGC NET (Life sciences) -Lectureship (AIR-32) (June 2012)
DBT-BET JRF - Category A list (AIR-51) (May 2012)
NIPER - Ph. D. ENTRANCE TEST (July 2012)
GATE (Biotechnology) (IIT Madras) (March 2011)
M. Tech (PTBT), NIPER Student Fellowship sponsored by DBT, Govt of India (August 2010)
NIPER-JEE (AIR-262) (July 2010)
GPAT (MSU Baroda) (AIR-680) (May 2010)
GATE (Pharmaceutical Sciences) (IIT Roorkee) (March 2009)
“IDMA J.B. Mody Best Students Excellence Awards for the Academic Year 2010” award from Indian Drugs Manufacturers Association (IDMA) (January 2012)
Received Gold Medal and certification award from Indian Pharmaceutical Association (IPA) for academic excellence (December 2010)
University Topper (NMU JALGAON) for four consecutive years of graduation (B. Pharm) and awarded with Gold Medal (March 2011)
Received scholarship for academic excellence from “Sir Ratan Tata Trust” for 3 years of graduation degree (2006 - 2009)
Received “Excellent Student Scholarship” from “Late Shri Mukesh Patel Memorial Trust” For 3 years of graduation degree for academic excellence (July 2006 - August 2009)
GALLERY
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The Fruits of Our Labor
LIST OF PUBLICATIONS
Peer-Reviewed Scientific Journals
Lavanika Roy, Pronamika Buragohain, Vivek Borse, “Strategies for The Sensitivity Enhancement in Point-of-Care Techniques”, Biosensors and Bioelectronics: X (companion journal of Biosensors and Bioelectronics – IF - 12.545), 10, 2021, 100098
A. Rajput, P. Pingale, D. Telange, S. Chalikwar, and Vivek Borse, “Lymphatic transport system to circumvent hepatic metabolism for oral delivery of lipid-based nanocarriers,” Journal of Drug Delivery Science and Technology, vol. 66, p. 102934, 2021 (IF - 5.062)
Jasmeen Kaur, Rohit Srivastava, Vivek Borse, “Recent Advances in Point-of-Care Diagnostics for Oral Cancer”, Biosensors and Bioelectronics, 178, 2021, 112995 (IF - 12.545)
Vivek Borse, “Nanodiagnostics: A Savior in COVID-19 Pandemic”, Journal of Applied Nanotechnology, 1, 2021, 1-4
Vivek Borse, Aditya Konwar, “Synthesis and characterization of gold nanoparticles as a sensing tool for the lateral flow immunoassay development”, Sensors International, 1, 2020, 100051
Vivek Borse, Aditya Konwar, Pronamika Buragohain, “Oral Cancer Diagnosis and Perspectives in India”, Sensors International, 1, 2020, 100046
Aditya Konwar, Vivek Borse, “Current status of point-of-care diagnostic devices in the Indian healthcare system with an update on COVID-19 pandemic” Sensors International, 1, 2020, 100015
Vivek Borse, Aditya Konwar, Rahul Jayant, Pravin Patil, “Perspectives of characterization and bioconjugation of gold nanoparticles, and their application in lateral flow immunosensing”, Drug Delivery and Translational Research, 10 (4), 2020, 878-902 (IF - 5.671)
P Giram and Vivek Borse, “Perspective of Doctoral Research in India”, Pharmaceutical Resonance, 3(1), 2020, 9-14
Mrunal Patil, Shashir Wanjare, Vivek Borse, Rohit Srivastava, Preeti Mehta, and Pradeep Vavia, “Arginolipid: A membrane‐active antifungal agent and its synergistic potential to combat drug resistance in clinical Candida isolates”, Arch Pharm Chem Life Sci - Archiv der Pharmazie, 353(1), 2020, 1900180, 1-13 (IF - 4.613)
Sounak Bagchi, Tanya Chhibber, Behnaz Lahooti, Angela Verma, Vivek Borse, and Rahul Dev Jayant, “In-vitro Blood-Brain Barrier Models for Drug Screening and Permeation Studies: An Overview", Drug Design, Development and Therapy, 13, 2019, 3591-3605 (IF - 4.319)
Pravin Patil, Gaurav Pandey, Ashwini Patil, Vivek Borse, Prashant Deshmukh, Dilip Patil, Rahul Tade, Sopan Nangare, Zamir Khan, Arun Patil, Mahesh More, M Veerapandian, and Sanjay Bari, “Graphene-based nanocomposites for sensitivity enhancement of surface plasmon resonance sensor for biological and chemical sensing: A review”, Biosensors and Bioelectronics, 139, 2019, 111324 (IF – 12.545)
Vivek Borse and Rohit Srivastava, “Process Parameter Optimization for Lateral Flow Immunosensing”, Materials Science for Energy Technologies, 2(3), 2019, 434-441 (Invited)
Vivek Borse and Rohit Srivastava, “Fluorescence lateral flow immunoassay-based point-of-care nanodiagnostics for orthopedic implant-associated infection”, Sensors and Actuators B: Chemical, 280, 2019, 24-33 (IF – 9.221)
Vivek Borse, Vaishali Pawar, Riya Thakkar, and Rohit Srivastava, “Dual-purpose injectable doxorubicin conjugated alginate gel containing polycaprolactone microparticles for anti-cancer and anti-inflammatory therapy”, Current Drug Delivery, 15 (5), 2018, 716-726 (IF – 3.758)
Vivek Borse, Adisha Kashikar, and Rohit Srivastava, “Fluorescence stability study of MPA-CdTe quantum dots in various biochemical buffers”, Journal of Nanoscience and Nanotechnology, 18, 2018, 2582-2591 (IF – 1.28)
Vivek Borse, Mukeshchand Thakur, Sohini Sengupta, and Rohit Srivastava, “N-doped multi-fluorescent carbon dots for ‘turn off-on’ silver-biothiol dual sensing and mammalian cell imaging application”, Sensors and Actuators B: Chemical, 248, 2017, 481-492 (IF – 9.221)
Vivek Borse, Paridhi Jain, Mayur Sadawana, and Rohit Srivastava, “‘Turn-on’ fluorescence assay for inorganic phosphate sensing”, Sensors and Actuators B: Chemical, 225, 2016, 340-347 (IF – 9.221)
Vivek Borse, Vaishali Pawar, Gautam Shetty, Arun Mullaji, and Rohit Srivastava, “Nanobiotechnology perspectives on prevention and treatment of orthopaedic implant associated infection”, Current Drug Delivery, 13 (2), 2016, 175-185 (IF – 3.758)
Ajay Suryavanshi, Vivek Borse, Vaishali Pawar, Sindhu KR, and Rohit Srivastava, “Material advancements in bone-soft tissue fixation devices”, Science Advances Today, 2, 2016, 25236
Conference Proceedings
Roshan Lal Makkar, Sana Syeda Aliya, Vivek Borse, and Rohit Srivastava, "Design and development of portable fluorescence reader using silicon photo multiplier (SiPM) sensor", Proc. SPIE 10680, Optical Sensing and Detection V, 106800B (Held at Strasbourg, France, May 9, 2018)
Vivek Borse, Abhaysinha Patil, and Rohit Srivastava, “Development and testing of portable fluorescence reader (PorFloR™)”, 498-501, Networked Healthcare Technology (NetHealth) Workshop, COMSNETS 2017, IEEE Xplore (Held at Bengaluru, India, January 8, 2017)
Vivek Borse, Mayur Sadawana, and Rohit Srivastava, “CdTe quantum dots: aqueous phase synthesis, stability studies and protein conjugation for development of biosensors”, 988423:1-12, Proc. SPIE 9884, Nanophotonics VI (Invited Research Paper for Conference proceedings- Held at Brussels, Belgium, April 19, 2016)
Vivek Borse, Abhishek Kaler, and Uttam Chand Banerjee, “Microbial synthesis of platinum nanoparticles and evaluation of their anticancer activity” International Conference on Recent Trends in Engineering and Technology, International Journal of Emerging Trends in Electrical and Electronics, Vol. 11, Issue 2, Page No. 26-31 (Invited Research Paper for Online Conference Proceedings, June 2015)
Book
Vivek Borse, Pranjal Chandra, and Rohit Srivastava (Eds.) “BioSensing, Theranostics, and Medical Devices: From Laboratory to Point-of-Care Testing”, Springer Nature, Singapore, 2022 (Book – ISBN - 978-981-16-2781-1) https://doi.org/10.1007/978-981-16-2782-8
Book Chapters
Vivek Borse, Jasmeen Kaur, and Rohit Srivastava, “Enzymatic biosensor platforms for diagnosis of heart diseases” (in progress), In: Patra S., Kundu D., Gogoi M. (Eds.) Enzyme-Based Biosensors: Recent Advances and Applications in Healthcare, Springer Nature, 2021 (Book Chapter - Invited)
Mukta Agrawal, Aditya Konwar, Amit Alexander, and Vivek Borse, “Nose to brain delivery of biological agents and stem cells”, In: Pardeshi C. and Souto E. (eds) Direct nose to brain drug delivery, Elsevier Inc. USA, 305-328, 2021 (Book Chapter - Invited)
Vivek Borse and Rohit Srivastava, “Nanobiotechnology Advancements in Lateral Flow Immunodiagnostics”, In: Chandra P., Prakash R. (eds) Nanobiomaterial Engineering, Springer, Singapore, 181-204, 2020 (Book Chapter - Invited)
Vivek Borse, Rohit Srivastava, and Aditya Konwar, “Nanobiotechnology Approaches for the Miniaturized Diagnostics”, In: Hussain C. M. (Ed.) “Handbook on Miniaturization in Analytical Chemistry”, Elsevier, 297-333, 2020 (Book Chapter - Invited)
Intellectual Property Rights
Patents
Rohit Srivastava, Vivek Borse, Vaishali Pawar, A Composite Comprising of Doxorubicin-Alginate Conjugate and Non-Steroidal Anti-Inflammatory Agent and Process for Preparation Thereof (Granted).
Design Registrations
Rohit Srivastava, Vivek Borse, Vartika Verma, UridSa - Urine Dip Strip Reader (Design application submitted: DES/BS/124303011-1/17-18), 08/05/2017
Rohit Srivastava, Vivek Borse, Abhaysinha Patil, Fluorescent Strip Reader - Electronic device for application in medical diagnostics (Design Registration No. 292001, 23/03/2017)
Trade Marks Registrations
Rohit Srivastava, Vivek Borse, ORACAN-D: Oral cancer detection (Registration No. 3232764, 11/04/2016, Trade Marks Journal No. 1872, 22/10/2018, Class 5)
Rohit Srivastava, Vivek Borse, Mayur Sadawana, Abhaysinha Patil, PorFloR - Portable Fluorescence Reader (Registration No. 3241959, 23/04/2016, Trade Marks Journal No. 1872, 22/10/2018, Class 10)
Rohit Srivastava, Vivek Borse, Vartika Verma, UridSa - Urine Dip Strip Reader (Application submitted: TM/BS/124303011-2/17-18), 08/05/2017
Rohit Srivastava, Vivek Borse, Vartika Verma, UridSa (Application submitted: TM/BS/124303011-1/17-18), 08/05/2017
Rohit Srivastava, Vivek Borse, PorColoR - Portable colorimetric strip reader (Registration No. 3304995, 08/07/2016, Trade Marks Journal No. 1774, 05/12/2016, Class 10)
Rohit Srivastava, Vivek Borse, Mayur Sadawana, Abhaysinha Patil, PorFloR - Portable Fluorescence Reader (Registration No. 3232763, 11/04/2016, Trade Marks Journal No. 1766, 10/10/2016, Class 10)
Rohit Srivastava, Vivek Borse, ORACAN-D: Oral cancer detection (Registration No. 3232765, 11/04/2016, Trade Marks Journal No. 1766, 10/10/2016, Class 10)
Rohit Srivastava, Vivek Borse, DEiCONT - Detection of ionic impurities in water (Registration No. 3232766, 11/04/2016, Trade Marks Journal No. 1766, 10/10/2016, Class 9)
Rohit Srivastava, Vivek Borse, Preclam-PCD - point of care diagnostic test kit for preeclampsia (Application submitted: TM/BS/124303011-1/16-17), 30/06/2016
EDITORIAL BOARD MEMBERSHIP
OPPORTUNITIES
PH. D. POSITIONS
Students interested in pursuing Ph. D. in the area of NanoBiosensors, NanoDiagnostics, Point-of-care Techniques, Medical Devices, Drug Delivery, and Biomaterials are welcome to apply.
Students with CSIR/UGC, DST-INSPIRE, DBT, ICMR, or GATE Fellowships are highly encouraged to apply.
RESEARCH PROJECT INTERNSHIPS AND COLLABORATIONS
Undergraduate/Postgraduate students interested/experienced in NanoBiosensors, NanoDiagnostics, Point-of-care Techniques, Medical Devices, Drug Delivery, and Biomaterials looking for Internship and JRF positions can apply.
Industrial/Academic collaborations are welcome for the research, technical expertise and consultancy.
CONTACT US
Department of Medical Devices
National Institute of Pharmaceutical Education And Research (NIPER) Hyderabad,
NH 9, Kukatpally Industrial Estate, Balanagar, Hyderabad, Telangana 500037 India